The study "Comparing the Effectiveness of Pre-filled Saline Flush Syringes in Maintaining Clinical Vascular Access" was conducted by Dr. Nguyen Van Phuc, BS.CKII, based on international clinical evidence and Vietnam Ministry of Health guidelines, to comprehensively compare single-use pre-filled saline flush syringes with the traditional manual preparation method (saline bottle, syringe, and separate needle).

1. Clinical research & Medical overview

Safety

The findings show that pre-filled saline flush syringes reduce the rate of central line-associated bloodstream infection by up to 77% compared with manual preparation, and reduce the rate of subcutaneous port-related bloodstream infection nearly 2.5-fold, from 6.3% down to 2.7%. The needle-free design of the product also completely eliminates the risk of needlestick injury to healthcare workers. A multicenter study of 3,853 catheters recorded a reduction in catheter failure rate from 57% to 43.4%. Regarding adherence to aseptic non-touch technique, the manual-preparation group breached this principle in as many as 72.3% of procedures, while the group using pre-filled syringes maintained significantly stricter control over procedural errors.

Economic efficiency

Manual preparation results in solution waste, including medications such as atropine and epinephrine, of 57% to 86%, while the waste rate with pre-filled syringes is 0%. Health-economic analysis shows that switching to pre-filled syringes saves healthcare systems millions of US dollars by reducing medication errors and lowering the cost of treating catheter-related infection complications.

Productivity

The use of pre-filled syringes reduces nursing resources spent on solution preparation and syringe management by up to 85%, allowing staff to focus more on direct patient care.

Conclusion

Single-use pre-filled saline flush syringes deliver comprehensive benefits across all four areas of safety, convenience, economic efficiency, and productivity. Leading health organizations worldwide recommend fully replacing solution draws from shared multi-dose bottles with single-dose, pre-filled systems. In Vietnam, the transition to pre-filled syringes should be prioritized in key departments such as Intensive Care, Emergency, Pediatrics, and Oncology - the areas where infection risk associated with vascular access and pressure on nursing time are both at their highest.

Key words

Pre-filled saline flush syringe, vascular access flush, catheter-related infection, injection safety, nursing resource optimization.

2. WEMSYIN Pre-Filled Flush Saline Syringes: A New Breakthrough in Infusion Therapy

Building on the medical evidence above, the shift toward single-dose, pre-filled systems is becoming an essential requirement for infection control in modern hospitals. In response to this urgent need within Vietnam's healthcare sector, WEMBLEY MEDICAL is proud to be a pioneering manufacturer of the WEMSYIN Pre-filled Saline Flush Syringe in Vietnam.

The product is used to flush peripheral intravenous catheters, peripherally inserted central catheters, central venous catheters, and implanted subcutaneous infusion ports, in order to maintain line integrity and prevent occlusion.

Technical & Clinical Standards

The WEMSYIN Pre-filled Saline Flush Syringe is a safe, convenient, time-saving solution that improves the efficiency of vascular access maintenance and catheter care in hospitals and clinics.

The product is researched and designed by WEMBLEY MEDICAL, manufactured on an automated production line in a Class 100,000 cleanroom, and controlled by an internationally certified quality management system, with the following key advantages

• Absolutely sterile and single-use, ensuring maximum safety for healthcare workers and patients.
• Made of medical-grade PP plastic, ensuring stable and accurate solution volume over time.
• Luer-lock connector generates a flushing pressure of ≥ 19.75 psi, effectively clearing all catheter types
• Available in a range of volumes, from 3 mL to 5 mL and 10 mL, offering flexibility for different clinical needs.

Advanced sterilization technology & specialized product classification

The product is manufactured on a new-generation automated production line in a certified Class 100,000 cleanroom, strictly controlled under global certification systems: ISO 13485:2016, GMP, and CE Marking.

Applying both advanced steam sterilization and ethylene oxide sterilization technologies, WEMBLEY MEDICAL offers two product lines to flexibly meet different clinical requirements.

• The WEMSYIN XS (Externally Sterile) line uses dual sterilization, achieving complete sterility of both the internal solution and the external surface of the syringe, and is specifically designed for high-sterility environments such as the operating room, the Intensive Care Unit, or procedures involving central catheters.
• The WEMSYIN SP (Sterile Path) line uses internal fluid-path sterilization, ensuring complete sterility of the 0.9% sodium chloride solution and the internal fluid pathway, and is suitable for environments that do not require surface sterility, serving routine peripheral line flushing across general wards.

For detailed product information, please contact our hotline at 028 7301 3688 for prompt assistance.

Source: "Comparing the Effectiveness of Pre-filled Saline Flush Syringes in Maintaining Clinical Vascular Access"